Common Health Question
Post-exposure prophylaxis (PEP) may stop you developing an HIV infection if you’ve been exposed to the virus. However, it doesn’t always work.
You may have been exposed to HIV if you've:
PEP is a course of anti-HIV medication. You must start the treatment as soon as possible after you’ve been exposed to HIV, ideally within a few hours. The medicines must be taken every day for four weeks.
PEP is unlikely to work if it’s started after 72 hours (three days) and it won’t usually be prescribed after this time.
PEP makes infection with HIV less likely. However, it’s not a cure for HIV and it doesn’t work in all cases. Some strains of HIV aren't affected by the medicines.
Also, the treatment may not work if you:
PEP can have severe side effects, such as:
If you’re already HIV-positive, but don’t know it, you could develop drug resistance to PEP if you don’t take your doses properly. This could limit your treatment options in the future.
PEP is only available on prescription. You can get PEP from:
However, PEP may not be available in all areas of England. GPs can't usually prescribe PEP.
When you request to have PEP, you’ll be asked some questions, such as:
You’ll be asked to take an HIV test before starting PEP treatment, to check whether you already have HIV. If you don’t agree to an HIV test, you won't be given PEP.
You’ll also need an HIV test after the treatment, to check that it’s been successful.
HIV can’t be cured. Don't rely on PEP to prevent HIV, because it doesn’t always work.