Health A to Z
Bronchiectasis is a long-term condition where the airways of the lungs become abnormally widened, leading to a build-up of excess mucus that can make the lungs more vulnerable to infection.
The most common symptoms of bronchiectasis include:
The severity of symptoms can vary widely. Some people have only a few symptoms that don't appear often, while others have wide-ranging daily symptoms.
The symptoms tend to get worse if you develop an infection in your lungs.
Read more about the symptoms of bronchiectasis.
You should see your GP if you develop a persistent cough. While this may not be caused by bronchiectasis, it requires further investigation.
If your GP suspects you may have bronchiectasis, they'll refer you to a specialist in treating lung conditions (a respiratory consultant) for further tests.
Read more about diagnosing bronchiectasis.
The lungs are full of tiny branching airways, known as bronchi. Oxygen travels through these airways, ends up in tiny sacs called alveoli, and from there is absorbed into the bloodstream.
The inside walls of the bronchi are coated with sticky mucus, which protects against damage from particles moving down into the lungs.
In bronchiectasis, one or more of the bronchi are abnormally widened. This means more mucus than usual gathers there, which makes the bronchi more vulnerable to infection. If an infection does develop, the bronchi may be damaged again, so even more mucus gathers in them, and the risk of infection increases further.
Over time, this cycle can cause gradually worsening damage to the lungs.
Bronchiectasis can develop if the tissue and muscles that surround the bronchi are damaged or destroyed.
There are many reasons why this may happen. The three most common causes in the UK are:
However, in many cases of bronchiectasis, no obvious cause for the condition can be found (known as idiopathic bronchiectasis).
Read more about the causes of bronchiectasis.
Bronchiectasis is thought to be uncommon. It's estimated that around 1 in every 1,000 adults in the UK have the condition.
It can affect anyone at any age, but symptoms don't usually develop until middle age.
Over 12,000 people were admitted to hospital in England during 2013-14 with bronchiectasis. The majority of these people were over 60 years old.
The damage caused to the lungs by bronchiectasis is permanent, but treatment can help relieve your symptoms and stop the damage getting worse.
The main treatments include:
Surgery is usually only considered for bronchiectasis in rare cases where other treatments haven't been effective, the damage to your bronchi is confined to a small area and you're in good general health.
Read more about the treatment of bronchiectasis.
Complications of bronchiectasis are rare, but they can be serious. One of the most serious complications is coughing up large amounts of blood, caused by one of the blood vessels in the lungs splitting. This problem can be life-threatening and may require emergency surgery to treat it.
Read more about the complications of bronchiectasis.
The outlook for people with bronchiectasis is highly variable and often depends on the underlying cause.
Living with bronchiectasis can be stressful and frustrating, but most people with the condition have a normal life expectancy. For people with very severe symptoms, however, bronchiectasis can be fatal if the lungs stop working properly.
Around 1,000 deaths reported in England and Wales each year are thought to be caused by bronchiectasis.
If you have bronchiectasis, your clinical team may pass information about you on to the National Congenital Anomaly and Rare Diseases Registration Service (NCARDRS).
This helps scientists look for better ways to prevent and treat this condition. You can opt out of the register at any time.
The most common symptom of bronchiectasis is a persistent cough that brings up a large amount of phlegm on a daily basis.
The phlegm can be clear, pale yellow or yellow-greenish in colour. Other people may only occasionally cough up small amounts of phlegm, or none at all.
Other symptoms may include:
If you develop a lung infection, your symptoms usually get worse within a few days. This is known as an infective exacerbation and it can cause:
You may also:
If you haven't previously been diagnosed with bronchiectasis and you develop a persistent cough, visit your GP for advice.
While persistent coughing may not necessarily be the result of bronchiectasis, it requires further investigation.
If you've been previously diagnosed with bronchiectasis and you begin to experience symptoms that suggest you have a lung infection, contact your GP. You'll usually need treatment with antibiotics.
Some people with bronchiectasis are given a stock of antibiotics as a precaution, in case they suddenly develop a lung infection.
Some people with bronchiectasis develop a severe lung infection that may need to be treated in hospital.
Signs and symptoms of serious lung infection include:
If you experience any of the above, phone the healthcare professional in charge of your care immediately. This may be your GP, a doctor who specialises in lung conditions (pulmonologist) or a specialist nurse.
Bronchiectasis is caused by the airways of the lungs becoming damaged and widened. This can be due to an infection or another condition. Sometimes, the cause is not known.
Your lungs are continually exposed to germs, so your body has sophisticated defence mechanisms designed to keep the lungs free of infection.
If a foreign substance (such as bacteria or a virus) gets past these defences, your immune system will attempt to stop the spread of any infection by sending white blood cells to the location of the infection. These cells release chemicals to fight the infection, which can cause the surrounding tissue to become inflamed.
For most people, this inflammation will pass without causing any further problems. However, bronchiectasis can occur if the inflammation permanently destroys the elastic-like tissue and muscles surrounding the bronchi (airways), causing them to widen.
The abnormal bronchi then become filled with excess mucus, which can trigger persistent coughing and make the lungs more vulnerable to infection. If the lungs do become infected again, this can result in further inflammation and further widening of the bronchi.
As this cycle is repeated, the damage to the lungs gets progressively worse. How quickly bronchiectasis progresses can vary significantly. For some people, the condition will get worse quickly, but for many the progression is slow.
In around half of all cases of bronchiectasis, no obvious cause can be found.
Some of the more common triggers that have been identified are described below.
Around a third of cases of bronchiectasis in adults are associated with a severe lung infection in childhood, such as:
However, as there are now vaccinations available for these infections, it is expected that childhood infections will become a less common cause of bronchiectasis in the future.
Around 1 in 12 cases of bronchiectasis occur because a person has a weakened immune system, which makes their lungs more vulnerable to tissue damage. The medical term for having a weakened immune system is immunodeficiency.
Some people are born with an immunodeficiency because of problems with the genes they inherit from their parents. It's also possible to acquire an immunodeficiency after an infection such as HIV.
Around 1 in 14 people with bronchiectasis develop the condition as a complication of an allergic condition known as allergic bronchopulmonary aspergillosis (ABPA).
People with ABPA have an allergy to a type of fungi known as aspergillus, which is found in a wide range of different environments across the world.
If a person with ABPA breathes in fungal spores, it can trigger an allergic reaction and persistent inflammation, which in turn can progress to bronchiectasis.
Aspiration is the medical term for stomach contents accidentally passing into your lungs, rather than down into your gastrointestinal tract. This is responsible for around 1 in 25 cases of bronchiectasis.
The lungs are very sensitive to the presence of foreign objects, such as small samples of food or even stomach acids, so this can trigger inflammation leading to bronchiectasis.
Cystic fibrosis is a relatively common genetic disorder, where the lungs become clogged up with mucus. The mucus then provides an ideal environment for a bacterial infection to take place, leading to the symptoms of bronchiectasis.
It is estimated that cystic fibrosis is responsible for around 1 in 33 cases of bronchiectasis.
Cilia are the tiny, hair-like structures that line the airways in the lungs. They are designed to protect the airways and help move away any excess mucus. Bronchiectasis can develop if there is a problem with the cilia that means they are unable to effectively clear mucus from the airways.
Conditions that can cause problems with the cilia include:
It's estimated that about 1 in every 33 cases of bronchiectasis are caused by Young's disease and 1 or 2 in every 100 cases are caused by primary ciliary dyskinesia.
However, as the regulations regarding the use of mercury are now much stricter than they were in the past, it is expected that Young’s syndrome will become a much less common cause of bronchiectasis in the future.
Certain conditions that cause inflammation in other areas of the body are sometimes associated with bronchiectasis, including:
These conditions are usually thought to be caused by a problem with the immune system, where it mistakenly attacks healthy tissue.
You should see your GP for advice if you develop a persistent cough, so they can look for a possible cause.
Your GP will ask you about your symptoms, such as how often you cough, whether you bring up any phlegm (sputum) and whether you smoke.
They may also listen to your lungs with a stethoscope as you breathe in and out. The lungs of people with bronchiectasis often make a distinctive crackling noise as a person breaths in and out.
If your GP thinks you may have a lung infection, they may take a sample of your phlegm, so it can be checked for bacteria.
If your GP suspects you could have bronchiectasis, you'll be referred to a doctor who specialises in treating lung conditions (a respiratory consultant) for further testing.
The maximum time you should have to wait for referral is 18 weeks, although you may not have to wait as long as this. Read more about waiting times.
Some of the tests a respiratory consultant may carry out to help diagnose bronchiectasis are described below.
Currently, the most effective test available to diagnose bronchiectasis is called a high-resolution computerised tomography (HRCT) scan.
A HRCT scan involves taking several X-rays of your chest at slightly different angles. A computer is then used to put all the images together. This produces a very detailed picture of the inside of your body and the airways inside your lungs (the bronchi) should show up very clearly.
In a healthy pair of lungs, the bronchi should become narrower the further they spread into your lungs, in the same way a tree branch separates into narrower branches and twigs.
If the scan shows that a section of airways is actually getting wider, this usually confirms bronchiectasis.
Other tests can be used to assess the state of your lungs and to try to determine what the underlying cause of your bronchiectasis may be.
These tests may include:
The damage to the lungs associated with bronchiectasis is permanent, but treatment can help prevent the condition getting worse.
In most cases, treatment involves a combination of medication, exercises you can learn and devices to help clear your airways. Surgery for bronchiectasis is rare.
There are a number of things you can do to help relieve the symptoms of bronchiectasis and stop the condition getting worse, including:
There are a range of exercises, known as airway clearance techniques, which can help to remove mucus from your lungs. This can often help improve coughing and breathlessness in people with bronchiectasis.
You can be referred to a physiotherapist, who can teach you these techniques.
The most widely used technique in the UK is called active cycle of breathing techniques (ACBT).
ACBT involves you repeating a cycle made up of a number of different steps. These include a period of normal breathing, followed by deep breaths to loosen the mucus and force it up; then you cough the mucus out. The cycle is then repeated for 20 to 30 minutes.
Don't attempt ACBT if you haven't first been taught the steps by a suitably trained physiotherapist, as performing the techniques incorrectly could damage your lungs.
If you're otherwise in good health, you'll probably only need to perform ACBT once or twice a day. If you develop a lung infection, you may need to perform ACBT on a more frequent basis.
Changing your position can also make it easier to remove mucus from your lungs. This is known as postural drainage.
Each technique can involve several complex steps, but most techniques involve you leaning or lying down while the physiotherapist or a carer uses their hands to vibrate certain sections of your lungs as you go through a series of "huffing" and coughing.
There are also a number of handheld devices that can help to remove mucus from your lungs.
Although these devices look different, most work in a similar way. Generally, they use a combination of vibrations and air pressure to make it easier to cough out any mucus.
Examples of these devices include the flutter, the RC cornet and the Acapella.
However, these devices aren't always available on the NHS, so you may have to pay for one yourself. They usually cost £45 to £60.
In some cases, medications to make breathing or clearing your lungs easier may be prescribed. These are discussed below.
Occasionally, medication inhaled through a device called a nebuliser may be recommended to help make it easier for you to clear your lungs.
Nebulisers are devices consisting of a face mask or mouthpiece, a chamber to convert the medication into a fine mist, and a compressor to pump the medication into your lungs.
A number of different medications can be administered using a nebuliser, including salt water solutions. These medications help to reduce the thickness of your phlegm so it's easier to cough it out. Nebulisers can also be used to administer antibiotics, if necessary (see below).
However, while the medications used with a nebuliser can be provided on prescription, the nebuliser device itself isn't always available on the NHS. In some areas, a local respiratory service may provide the device without charge, but if this isn't an option, you may have to pay for a device.
If you have a particularly severe flare-up of symptoms, you may be prescribed bronchodilator medications on a short-term basis.
Bronchodilators are inhaled medications that help make breathing easier by relaxing the muscles in the lungs. Examples of this type of medication include beta2-adrenergic agonist, anticholinergics and theophylline.
If you experience a worsening of symptoms because of a bacterial infection (known as an "infective exacerbation") then you'll need to be treated with antibiotics.
A sample of phlegm will be taken to determine what type of bacteria is causing the infection, although you'll be initially treated with an antibiotic known to be effective against a number of different bacteria (a broad spectrum antibiotic) because it can take a few days to get the test results.
Depending on the test results, you may be prescribed a different antibiotic, or in some cases, a combination of antibiotics known to be effective against the specific bacteria causing the infection.
If you're well enough to be treated at home, you'll probably be prescribed two to three antibiotic tablets a day for 10-14 days. It's important to finish the course even if you feel better, as stopping the course prematurely could cause the infection to recur quickly.
If your symptoms are more severe (see symptoms of bronchiectasis for a detailed description) you may need to be admitted to hospital and treated with antibiotic injections.
If you have three or more infective exacerbations in any one year, or your symptoms during an infective exacerbation were particularly severe, it may be recommended that you take antibiotics on a long-term basis. This can help to prevent further infections and give your lungs the chance to recover.
This could involve taking low-dose antibiotic tablets to minimise the risk of side effects, or using an antibiotic nebuliser (see above for more information about nebulisers).
Using antibiotics in this way does increase the risk that one or more types of bacteria will develop a resistance to the antibiotic. Therefore, you may be asked to give regular phlegm samples to check for any resistance. If bacteria do show signs of developing a resistance, then your antibiotic may need to be changed.
Surgery is usually only recommended where bronchiectasis is only affecting a single section of your lung, your symptoms aren't responding to other treatment and you don't have an underlying condition that could cause bronchiectasis to recur.
The lungs are made up of sections known as lobes – the left lung has two lobes and the right lung has three lobes. Surgery for focal bronchiectasis would usually involve removing the lobe affected by the bronchiectasis in a type of operation known as a lobectomy.
Surgery won't be used if more than one lobe is affected, as it’s too dangerous to remove so much lung tissue.
In some cases, people with bronchiectasis can develop serious complications that require emergency treatment.
A rare, but serious, complication of bronchiectasis is coughing up large amounts of blood (the medical term for this is massive haemoptysis). This can occur when a section of one of the blood vessels supplying the lungs suddenly splits open.
Symptoms that may indicate massive haemoptysis include:
Massive haemoptysis is a medical emergency. If you think someone is experiencing massive haemoptysis, then call 999 for an ambulance.
A person with massive haemoptysis needs to be admitted to hospital and a tube may need to be placed into their throat to assist them with their breathing.
A procedure called a bronchial artery embolisation (BAE), carried out by specialist radiology doctors, will then be required to stop the bleeding. During a BAE, a special dye is injected into your arteries so they show up clearly on X-rays.
Then, using X-ray scans as a guide, the source of the bleeding is located and injected with tiny particles, around the size of a grain of sand, that will help clog the vessel up and stop the bleeding.